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Imaging Clinical Trials.
Though much is written on the subject of Clinical Trials, this Wiki is a unique resource for imaging professionals who need more than just superficial familiarity with design and conduct of clinical trials. This resource distills the key modules of a remarkable mentoring program conducted for the past several years by the RSNA and NCI for a limited number of selected young imaging faculty members who wish to become polished clinical trialists.
Consult the User's Guide for information on using the wiki software.
Abbreviations and Definitions
RR (Response Rate)represents data that implies an attenuation of the amount of tumor burden realtive to the degree present at baseline and can include either reduced symptoms or shrinkage of measured tumor size.
ORR (Objective Response Rate)in solid tumors represents measurable reduction in the dimension of target tumor masses when depicted on imaging
CR (Complete Response)
PR (Partial Response)
SD (Stable Disease)
PD (Progressive Disease)
Key external links
Essential Software
Acrobat Professional – extract text (Select Tool) and images (Advanced ->export all images); track changes (Comments & Markup); publish a smaller, unchangeable PPT as a PDF;
Word – Convert to Adobe PDF using an Acrobat plug-in; Track changes (ctrl+shift+E); email document as a draft for comment; add images; has hierarchical outline view Try it
Endnote – links to Word; does its’ own PUbmed searching, constructs a complete bibliography. and dynamically formats your references while you write
PowerPoint (PPT) – you can incorporate and edit web pages and images for presentations
Quosa – http://www.quosa.com/ Connects automatically to PubMed and extracts full article PDFs if institutionally licensed