Difference between revisions of "Main Page"
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<big>'''Imaging Clinical Trials.'''</big> | <big>'''Imaging Clinical Trials.'''</big> | ||
| − | Though much is written on the subject of Clinical Trials, this Wiki is a | + | Though much is written on the subject of Clinical Trials, this Wiki is a resource for imaging professionals who need more than superficial familiarity in the design and conduct of clinical trials. It is an extract of the key modules of a remarkable mentoring program conducted for the past several years by the RSNA and NCI for select young imaging faculty who wish to become professional clinical trialists. |
Consult the [http://meta.wikimedia.org/wiki/Help:Contents User's Guide] for information on using the wiki software. | Consult the [http://meta.wikimedia.org/wiki/Help:Contents User's Guide] for information on using the wiki software. | ||
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== Abbreviations and Definitions == | == Abbreviations and Definitions == | ||
| − | RR (Response Rate) represents data that implies an attenuation of the amount of tumor burden realtive to the degree present at baseline and can include either reduced symptoms or shrinkage of measured tumor size. | + | '''RR''' (Response Rate) represents data that implies an attenuation of the amount of tumor burden realtive to the degree present at baseline and can include either reduced symptoms or shrinkage of measured tumor size. |
| − | ORR (Objective Response Rate)in solid tumors represents measurable reduction in the dimension of target tumor masses when depicted on imaging | + | '''ORR''' (Objective Response Rate)in solid tumors represents measurable reduction in the dimension of target tumor masses when depicted on imaging |
| − | CR (Complete Response) | + | '''CR''' (Complete Response) |
| − | PR (Partial Response) | + | '''PR''' (Partial Response) |
| − | SD (Stable Disease) | + | '''SD''' (Stable Disease) |
| − | PD (Progressive Disease) | + | '''PD''' (Progressive Disease) |
== Key out-of-Wiki Links == | == Key out-of-Wiki Links == | ||
Revision as of 02:10, 21 December 2007
Imaging Clinical Trials.
Though much is written on the subject of Clinical Trials, this Wiki is a resource for imaging professionals who need more than superficial familiarity in the design and conduct of clinical trials. It is an extract of the key modules of a remarkable mentoring program conducted for the past several years by the RSNA and NCI for select young imaging faculty who wish to become professional clinical trialists.
Consult the User's Guide for information on using the wiki software.
Abbreviations and Definitions
RR (Response Rate) represents data that implies an attenuation of the amount of tumor burden realtive to the degree present at baseline and can include either reduced symptoms or shrinkage of measured tumor size.
ORR (Objective Response Rate)in solid tumors represents measurable reduction in the dimension of target tumor masses when depicted on imaging
CR (Complete Response)
PR (Partial Response)
SD (Stable Disease)
PD (Progressive Disease)
Key out-of-Wiki Links
- List of Cancers. http://www.cancer.gov/cancertopics/alphalist
- PDQ. http://www.cancer.gov/cancertopics/pdq peer-reviewed summaries of cancer treatment, screening, genetics and a clinical trials directory
- Learning about Clinical Trials. http://www.cancer.gov/clinicaltrials/learning
- Search for Clinical Trials. http://www.cancer.gov/search/clinicaltrials
- Conducting Clinical Trials http://www.cancer.gov/clinicaltrials/conducting
- NCI Cancer Therapy Evaluation Program (CTEP) http://ctep.cancer.gov
- NCI Cancer Imaging Program http://imaging.cancer.gov
Essential Software
You can't be efficient until you have a thorough knowledge of the following software applications. Spend some time learning them intimately - it will be worth it.
Acrobat Professional – especially when you need to extract text (Select Tool) and images (Advanced ->export all images); track changes (Comments & Markup); or publish a smaller, unchangeable PPT as a PDF;
Word – convert to Adobe PDF using an Acrobat plug-in; Track changes (ctrl+shift+E); email document as a draft for comment; add images; has hierarchical outline view
Endnote – links to Word; does its’ own PUBmed searching, constructs a complete bibliography and dynamically formats your references while you write
PowerPoint (PPT) – you can incorporate and edit web pages and images for presentations. And it's an easy way to construct protocol flow schemas
Quosa – http://www.quosa.com/ connects automatically to PubMed and extracts full article PDFs if you are allowed to do so by your institutional license.
Informed Consent
Informed consent is an essential part of the ethical conduct of clinical trials.